Department: Clinical Neurosciences
Location: Southampton General Hospital
Salary: £30,942 to £38,017 Per annum
Full Time Fixed Term (until 30/04/2022)
Interview Date: To be confirmed
Applications are invited for a Post-Doctoral researcher to join Dr Self’s paediatric eye research group to study potential novel treatments for infants with Albinism.
You will have a PhD* or equivalent professional qualifications and experience in cell biology and/or pigment research and/or high-throughput therapeutic studies.
Previous experience in one of the following is essential, and more than one is desirable: cell biology / molecular biology / cellular/in-vitro disease modelling / the study of pigment disorders / highthroughput drug screening AND genetics.
A background in vision research or pigment research or high-throughput therapeutic studies in rare disease would be desirable but is not essential.
You should be a highly motivated candidate, capable of independently designing and carrying out experiments as well as intellectually contributing to the project in a timely manner.
You should be interested in the interface between lab-based research and clinical research and ideally, have an interest in paediatric disorders.
Evidence of publishing in high-quality, peer-reviewed journals would be desirable.
The Self group investigates various aspects of paediatric eye disease from very clinical projects with a team of research orthoptists to lab-based and genetic studies in-house and through collaborations with other PI’s in the vision research group.
This project, funded by the Gift of Sight Appeal, will provide an opportunity to lead a new study seeking to evaluate a range of potential therapeutics as treatments for infants with forms of Albinism.
The study has the potential to identify and validate a range of novel therapeutics and take preliminary findings through to clinical studies and trials in the future (as we have recently done with LDOPA).
The project will employ multiple techniques including cell culture-disease modelling, molecular biology/biochemistry, confocal and ultrastructural imaging, high throughput drug screening and some genetics work.
This exciting project offers the b opportunity to work at the interphase of cutting-edge, multidisciplinary research.
You will join a vibrant research group and be expected to work as a team with other postdocs, PhD/undergraduate students, clinician-scientists and technicians in the wider research group.
You will collaborate with colleagues across Faculties of Medicine and Biological Sciences at the University of Southampton and colleagues in other institutions.
The candidate can expect a research-focused environment with mentoring and career development support from the PI and co-supervisors (Dr Arjuna Ratnayaka and Miss Helena Lee).
The post is fixed term until 30/04/2022 .
Interviews for shortlisted candidates are likely to be held in March/April 2020. Informal inquires may be directed to Mr Jay Self
A standard DBS check is required for this role.
Upon appointment you will be given the title of Research Fellow. If you have not yet been awarded your PhD please see the below information.
*Applications will be considered from candidates who are working towards a relevant PhD qualification. The title of Research Fellow will be applied upon completion of PhD. Prior to the qualification being awarded the title of Senior Research Assistant will be given.
You should submit your completed application form online at www.jobs.soton.ac.uk.
The application deadline will be midnight. If you need any assistance, please call Steff Palmer (Recruitment Team) on +44 (0) 23 8059 4560.