Research Associate EPICut Project
Job number ACAD104377
Division/School - School of Biochemistry
Contract type - Open Ended
Working pattern - Full time
Salary £33,797 - £38,017 per annum
Closing date for applications - 24th January 2020
EPICut project: A postdoc position is available as part of a prestigious ERC advanced grant to Prof. Mark Szczelkun.
The ambition of the EPICut project is to understand the structural and mechanistic basis for how a diverse set of prokaryotic Type IV restriction systems cleave epigenetic modifications on mobile genetic elements such as phage.
We are looking for a talented and enthusiastic individual who can use protein biochemistry, biophysical assays and/or single molecule techniques to investigate the mechanisms of modified DNA recognition and cleavage.
You will join an established and well-funded research lab in the DNA-Protein Interactions Unit, with access to biophysical equipment including stopped flow, ITC, etc, as well as TIRF, optical tweezers and magnetic tweezers microscopes.
The role will involve the day-to-day project management, collaborations with other members of the EPICut project (a PDRA and technician in Bristol, and a PDRA in Exeter), and assisting with training and supervision of postgraduate/undergraduate students.
A PhD in protein biochemistry, biophysics, or a related subject is essential (awarded or imminent). Previous experience of the following is desirable, but training can be provided: analysis of protein-DNA interactions; enzymology; single-molecule microscopy; construction of microscopes.
You will be highly organised, and eager to learn new skills and to interact with a broad range of colleagues.
The grant end date is 31 July 2023.
For more information please see: www.bristol.ac.uk/brissynbio/people/mark-d-szczelkun/overview.html.
For informal enquiries please contact Professor Mark Szczelkun, tel: +44 (0)117 331 2158, email: Mark.Szczelkun@bristol.ac.uk.
We welcome applications from all members of our community and are particularly encouraging those from diverse groups, such as members of the LGBT+ and BAME communities, to join us.
Click Here to Apply