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Research Associate - Biochemistry

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University of Bristol
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Research Associate EPICut Project
Job number ACAD104377
Division/School - School of Biochemistry
Contract type - Open Ended
Working pattern - Full time
Salary 33,797 - 38,017 per annum
Closing date for applications - 24th January 2020

EPICut project: A postdoc position is available as part of a prestigious ERC advanced grant to Prof. Mark Szczelkun.

The ambition of the EPICut project is to understand the structural and mechanistic basis for how a diverse set of prokaryotic Type IV restriction systems cleave epigenetic modifications on mobile genetic elements such as phage.

We are looking for a talented and enthusiastic individual who can use protein biochemistry, biophysical assays and/or single molecule techniques to investigate the mechanisms of modified DNA recognition and cleavage.

You will join an established and well-funded research lab in the DNA-Protein Interactions Unit, with access to biophysical equipment including stopped flow, ITC, etc, as well as TIRF, optical tweezers and magnetic tweezers microscopes.

The role will involve the day-to-day project management, collaborations with other members of the EPICut project (a PDRA and technician in Bristol, and a PDRA in Exeter), and assisting with training and supervision of postgraduate/undergraduate students.

A PhD in protein biochemistry, biophysics, or a related subject is essential (awarded or imminent). Previous experience of the following is desirable, but training can be provided: analysis of protein-DNA interactions; enzymology; single-molecule microscopy; construction of microscopes.

You will be highly organised, and eager to learn new skills and to interact with a broad range of colleagues.

The grant end date is 31 July 2023.

For more information please see:

For informal enquiries please contact Professor Mark Szczelkun, tel: +44 (0)117 331 2158, email:

We welcome applications from all members of our community and are particularly encouraging those from diverse groups, such as members of the LGBT+ and BAME communities, to join us.

Click Here to Apply

Status: Research Scientist
Location: Bristol, UNITED KINGDOM
Advert Published: 6 Jan 2020
Expiry date: 5 Feb 2020
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