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Research Associate - how proteins interact with methylated DNA and other modifications

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University of Bristol


School of Biochemistry

£32,528 - £34,520 per annum

Understanding how proteins interact with methylated DNA and other modifications.

A postdoctoral research position is available in the group of Professor Mark Szczelkun at the School of Biochemistry, University of Bristol, UK. The post is for 12 months and is funded as part of BrisSynBio, a multi-disciplinary research centre that focuses on the biomolecular design and engineering aspects of synthetic biology,and has been established as one of six Synthetic Biology Research Centres in the UK. The project is titled “Towards re-engineering tools for binding epigenetic markers”,and seeks to examine how the bacterial Type IV restriction enzymes search for methylated DNA sites, and how they recognise the DNA modification through base flipping.

For this post, you will have a background in biochemistry, biophysics, or a related area. You should also show a demonstrable interest in enzyme/molecular genetic research. Quantitative skills, and experience in protein enzymology, fluorescence spectroscopy, single molecule microscopy and/or in vitro evolution techniques would be advantageous. You will be expected to work in collaboration with the other members of the DNA-Protein Interactions Unit

The successful candidate will hold, or expect to hold shortly, a PhD in biochemistry or a related area. This position will be attractive to a highly motivated individual with a keen interest in biophysical science.

The closing date for applications is 23.59 on 10th June 2018.

The anticipated interview date is Monday 25th June 2018

The University is committed to creating and sustaining a fully inclusive culture. We welcome applicants from all backgrounds and communities.

Click Here To Apply

Status: Research Scientist
Location: Bristol, UNITED KINGDOM
Advert Published: 12 May 2018
Expiry date: 10 Jun 2018
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